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Global Idiopathic Pulmonary Fibrosis (IPF) Market (2023 Edition): Analysis By Drug Type (Pirfenidone, Nintedanib, Others), Route of Administration (Oral, Parenteral, Others), Distribution Channel, By Region, By Country: Market Insights and Forecast (2019-2029)

Category: Healthcare and Pharmaceutical

Publish Date: July 2023

No. of Pages: 260

Format: Pdf

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What is Idiopathic Pulmonary Fibrosis?

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic lung disease marked by the stiffening (fibrosis) of the lungs for unexplained reasons. The term "idiopathic" indicates that the disease's precise cause is unknown.

In IPF, the lung tissue is gradually thickened, rigid, and scarred, impairing the lungs' capacity to expand and contract normally. This fibrosis and the subsequent loss of lung function can result in a variety of symptoms, including a chronic dry cough, shortness of breath, exhaustion, and chest pain. Typically, the symptoms develop and worsen progressively.

Idiopathic Pulmonary Fibrosis Market Overview

The Idiopathic Pulmonary Fibrosis Market is expected to witness an exponential growth rate at CAGR of 12.61% during the period 2024 to 2029. The market is valued at USD 4393.72 Million in 2022 which is expected to reach USD 10638.61 Million in 2029. The global Idiopathic Pulmonary Fibrosis market is expected to grow in the coming years, driven by several factors such as the increasing ageing population, growing smoking population and increasing number of lung diseases.

Pharmaceutical companies are making investments in research and development to identify new IPF treatments. Currently, clinical trials are being conducted on a number of drugs that target different mechanisms implicated in the progression of IPF. Among these are antifibrotic agents, immunomodulatory pharmaceuticals, and innovative therapeutic approaches.

Increasing number of geriatric population. 

The prevalence of Idiopathic Pulmonary Fibrosis increases with age, and a significant proportion of those afflicted are elderly. The global geriatric population is growing, primarily due to increased life expectancy and declining fertility rates. 

The World Health Organization predicts that the number of people aged 60 and older will more than double by 2050. This demographic shift suggests a larger consumer base for Idiopathic Pulmonary Fibrosis-related goods and services. The aging population has a direct effect on the industry by increasing the demand for effective healthcare and management solutions.

Limited therapeutics and treatment options

The goal of the medications that are currently available for idiopathic pulmonary fibrosis (IPF), such as pirfenidone and nintedanib, is not to cure the condition but rather to cease the disease's progression. Although these treatments have demonstrated some benefit in delaying the deterioration of lung function and the advancement of the disease, they are not a total solution to the problem. This limitation can have a negative effect on patient outcomes and contribute to dissatisfaction, as both patients and physicians seek more effective treatments.

Segment-Wise Insights

Pirfenidone segment accounts for USD 2259.30 Million in 2022

Pirfenidone is an antifibrotic drug that has been licensed for the treatment of idiopathic pulmonary fibrosis (IPF) in a number of countries, including the United States, the European Union, and Japan. Oral medicine targets numerous lung fibrotic pathways.

Pirfenidone may have anti-inflammatory, antioxidant, and antifibrotic actions, but its mechanism is unknown. It inhibits TGF-β and TNF-α, pro-inflammatory and pro-fibrotic substances. Pirfenidone reduces inflammation and fibrosis to delay IPF and preserve lung function.

Regional Insights   

According to Azoth Analytics Estimates, Americas accounts for the largest revenue share in 2022. Factors driving the growth of the market include a growing aging population, increasing awareness about lung health, and advancements in screenings and diagnostic technology. Europe Idiopathic Pulmonary Fibrosis Market is the fastest growing market with a positive outlook for the future, driven by factors such as an large smoking population, increasing awareness about Idiopathic Pulmonary Fibrosis, and advancements in development of novel therapeutics.

Competitive Landscape

Global Idiopathic Pulmonary Fibrosis Market is fragmented with top 10 companies accounting for a significant revenue share in the year 2022. Leading companies and brands in the market are executing different strategies and partnerships to strengthen the foothold and increase the competitiveness and product offerings in the market.

F. Hoffmann-La Roche AG, Cipla Ltd., Bristol-Myers Squibb Co., and Boehringer Ingelheim among others are the leading companies in the Global Idiopathic Pulmonary Fibrosis Market.

Leading companies in the Global Idiopathic Pulmonary Fibrosis Market include:

Boehringer Ingelheim

F. Hoffmann-La Roche AG

Cipla Ltd. 

Shionogi & Co., Ltd. 

Bristol-Myers Squibb Co. 

United Therapeutics 

FibroGen, Inc. 

Pliant Therapeutics 

Galecto Inc. 

CSL Behring 

Strategic Developments in the Idiopathic Pulmonary Fibrosis Market

  • June, 2021: Boehringer Ingelheim announced its acquisition of Abexxa Biologics for the research and development of cancer immunotherapies.
  • February, 2023: Shionogi & Co., Ltd announced a Joint venture with Accenture to improve business process efficiency. 

Segmentations in the Report

By Indication 

  • Pirfenidone
  • Nintedanib
  • Other drugs

 By Molecule Type

  • Oral
  • Parenteral
  • Other ROA

 By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Channel

 By Region

  • Americas
  • Europe
  • Asia-Pacific
  • Middle East & Africa

 

Frequently Asked Questions

What is the expected market value of Idiopathic Pulmonary Fibrosis Market in 2029?

Global Idiopathic Pulmonary Fibrosis Market is expected to be valued at USD 10638.61 Million in 2029. 

At what growth rate is Idiopathic Pulmonary Fibrosis Market expected to grow in the forecast period?

During 2024-2029, Idiopathic Pulmonary Fibrosis Market is expected to grow at CAGR of 12.61%.

Which Region dominates the Idiopathic Pulmonary Fibrosis Market?

Americas contributes the largest revenue share in the Idiopathic Pulmonary Fibrosis Market.

At what rate will Americas Idiopathic Pulmonary Fibrosis Market Grow?

During 2024-2029, Americas Idiopathic Pulmonary Fibrosis Market is expected to grow at a CAGR of 11.98%.

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